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OSu-Glu-VC-PAB-MMAE Size:1mg A Study Evaluating the Efficacy

SKU 39237144606
4.8
USD200.00 USD246.00

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Description

A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant

32 Purity (HPLC) >= 95% Solubility DMSO

It binds to the VHL E3 ligase with an IC50 of 0

379 SMILES OCCCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It reacts with thiol compounds such as amino acid

OSu-Glu-VC-PAB-MMAE Size:1mg A Study Evaluating the EfficacySuO Glu Val Cit PAB MMAE (NHS Glutarate Val Cit PAB MMAE) is a cleavable ADC linkerpayload system consisting of a SuO Glu Val Cit PAB peptide linker and the microtubule disrupting cytotoxic payload MMAE. This ADC building block is widely used in the synthesis of antibody drug conjugates for cancer research, where the Val Cit PAB motif enables enzyme cleavable release of MMAE inside target cells, supporting highly potent, targeted delivery in

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