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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme 426 SMILES OCCCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

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Description

426 SMILES OCCCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

333 SMILES: OC(=O)CCC(=O)N1CC2=CC=CC=C2C#CC2=C1C=CC=C2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name Rapamycin-LC-fluorescein Synonyms C40-(Glycyl-6-hexanoic-(5(6)-Carboxamidofluorescien))-rapamycin CAS Number 1263034-82-7 Related CAS Molecular Formula C80H105N3O21 Molecular Weight 1444

and stable

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan enzyme 426 SMILES OCCCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is

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