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Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan cr6g 36 SMILES Cl

SKU 90084868360
4.2
USD495.00 USD531.00

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Description

36 SMILES Cl

Product Name Phthalimidinoglutarimide-C3-O-PEG4-OH Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG4-OH CAS Number n/a Related CAS Molecular Formula C24H34N2O8 Molecular Weight 478

15 SMILES Cl

HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation

Its exceptional stability and versatility make it a cornerstone in applications like medical imaging

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan cr6g 36 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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