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Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg dCeMM1 is a glue degrader

SKU 87944582257
4.8
EUR495.00 EUR530.00

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Description

dCeMM1 is a glue degrader of RBM39 that functions by re-directing the activity of the CRL4DCAF15 ligase

Product Name: Cy3 alkyne monosulfo Synonyms: Cy3 alkyne

Excitation maximum = 500 nm

References

458 SMILES [N-]=[N+]=NCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg dCeMM1 is a glue degraderSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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