Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE gly Product Name 6-(methoxy-d3)pyridin-3-amine Synonyms 6-(²H3)methoxypyridin-3-amine

Product Name 6-(methoxy-d3)pyridin-3-amine Synonyms 6-(²H3)methoxypyridin-3-amine CAS Number 1202760-61-9 Related CAS Molecular Formula C6H8N2O Molecular Weight 127

Product Name Pomalidomide-CO-C6-Br Synonyms Pomalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H22BrN3O5 Molecular Weight 464

By combining P1 and P18

85 SMILES Cl

HaXS8 bridges HaloTag and SNAP-tag fusion proteins by reacting covalently with their respective active sites: the chloroalkane binds irreversibly to HaloTag’s modified dehalogenase pocket

Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE gly Product Name 6-(methoxy-d3)pyridin-3-amine Synonyms 6-(²H3)methoxypyridin-3-amineSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate