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Structural basis for the action of the drug trametinib at KSR-bound MEK
Product Name Pomalidomide-CO-C3-azide Synonyms Pomalidomide-4'-CO-C3-azide CAS Number 2227423-22-3 Related CAS Molecular Formula C17H16N6O5 Molecular Weight 384
Ready for conjugation to a target protein ligand to form PROTACs containing 5'-substituted Lenalidomide as cereblon ligand
252 SMILES BrCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
NCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
dCeMM2 ptotac ligand Structural basis for the actiondCeMM2 (Compound 2) is a glue degrader. dCeMM2 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12 cyclin K with a CRL4B ligase complex. Product Name dCeMM2 Synonyms CAS Number 296771 07 8 Related CAS Molecular Formula C16H11ClN6OS Molecular Weight 370. 82 SMILES ClC1=CC=C(NC(=O)CSC2=NN=C3C(NC4=CC=CC=C34)=N2)N=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF Shipping Conditions Room
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