Pay in 4 interest-free payments of $111.25 Learn more
Ships within 48 hours · Estimated delivery Aug 26 - Aug 31
BCN reacts efficiently with azides to form stable 1
linking two molecules covalently
CP-Tetrazine is a SNAP-tag substrate containg a methayltetrazine group for click chemistry applications
and radiotherapeutic agents
NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan acid-acid BCN reacts efficiently with azidesSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
