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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP coumarin Product Name Lenalidomide-CO-PEG1-OH Synonyms Lenalidomide-4'-CO-PEG1-OH

SKU 73247282968
4.4
EUR445.00 EUR494.00

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Description

Product Name Lenalidomide-CO-PEG1-OH Synonyms Lenalidomide-4'-CO-PEG1-OH CAS Number n/a Related CAS Molecular Formula C16H17N3O5 Molecular Weight 331

Product Name tert-butyl 4-(3-aminopropyl)piperazine-1-carboxylate Synonyms 1-Boc-4-(3-aminopropyl)piperazine CAS Number 373608-48-1 Related CAS Molecular Formula C12H25N3O2 Molecular Weight 243

Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C79H110FN11O26 Molecular Weight 1648

68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Single isomer 6-FAM ethylenediamine

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP coumarin Product Name Lenalidomide-CO-PEG1-OH Synonyms Lenalidomide-4'-CO-PEG1-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload

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