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Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg and it can be well

SKU 72491626804
4.4
USD445.00 USD468.00

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Description

and it can be well excited by 568 nm line of the Ar-Kr mixed gas laser that is used in many confocal laser-scanning microscopes

Product Name Phthalimidinoglutarimide-propargyl-PEG2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG2-OH CAS Number n/a Related CAS Molecular Formula C20H22N2O6 Molecular Weight 386

Product Name MaP555-Maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C33H34N6O7S Molecular Weight 658

196 SMILES: [2H]C([2H])([2H])C(=O)C1=CC=C(C)C=C1 Isotopic Enrichment: 98 atom % D Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg and it can be wellSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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