Azide-Dap(m-PEG4)-Val-Ala-PAB Size:25mg Product Name Thalidomide Synonyms Pomalyst

Product Name Thalidomide Synonyms Pomalyst CAS Number 50-35-1 Related CAS Molecular Formula C13H10N2O4 Molecular Weight 258

045 Purity (HPLC) >= 95% Solubility DMSO

also referred to as the Cu(I)-catalyzed free click reaction

m-PEG8 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility

85 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Dap(m-PEG4)-Val-Ala-PAB Size:25mg Product Name Thalidomide Synonyms PomalystSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine