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including biomolecules containing azide groups through copper catalyzed azide-alkyne cycloaddition (CuAAC)
Ispinesib is an autophagic molecular degrader
Product Name: 5-TAMRA Synonyms: 5-Carboxytetramethylrhodamine CAS Number: 91809-66-4 Molecular Formula: C25H22N2O5 Molecular Weight: 430
The water soluble 6-FAM PEG3 azide has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal azide group
378 SMILES O=C(CCCC#C)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium including biomolecules containing azide groupsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU
