DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde Product Name Thalidomide-O-C4-OH Synonyms Thalidomide-4'-O-C4-OH

Product Name Thalidomide-O-C4-OH Synonyms Thalidomide-4'-O-C4-OH CAS Number 2636072-82-5 Related CAS Molecular Formula C17H18N2O6 Molecular Weight 346

821 Purity (HPLC) >= 95% Solubility DMSO

OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCC#C)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

including anticancer

97 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)NCCCN=[N]#N)C3=CC=C(C=C3C2(C)C)S(O)(=O)=O)N(CCCS([O-])(=O)=O)C2=CC=C(C=C12)S(O)(=O)=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde Product Name Thalidomide-O-C4-OH Synonyms Thalidomide-4'-O-C4-OHSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate