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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor 308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC)

SKU 64416407419
4.5
EUR345.00 EUR387.00

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Description

308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes

S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616

Product Name Phthalimidinoglutarimide-C4-Br Synonyms Phthalimidinoglutarimide-4'-C4-Br CAS Number n/a Related CAS Molecular Formula C17H19BrN2O3 Molecular Weight 379

4 SMILES OC(=O)CCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor 308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine

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