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DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
Product Name Phthalimidinoglutarimide-C4-OH Synonyms Phthalimidinoglutarimide-4'-C4-OH CAS Number 2207541-24-8 Related CAS Molecular Formula C17H20N2O4 Molecular Weight 316
Product Name Thalidomide-5'-C6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C19H22N2O5 Molecular Weight 358
CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide
339 SMILES OCCCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
DOTA-C5-propanamido-maleimide aminel DCAF1-based PROTACs with activity againstDOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA C5 propanamido maleimide Synonyms CAS Number n a Related CAS Molecular Formula C28H45N7O10
