DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Product Name CP-BCN Synonyms SNAP2-BCN

Product Name CP-BCN Synonyms SNAP2-BCN CAS Number Related CAS Molecular Formula C23H25ClN4O3 Molecular Weight 440

Product Name DOTA-butyne Synonyms CAS Number 2125661-62-1 Related CAS Molecular Formula C20H33N5O7 Molecular Weight 455

eLife 2018

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name BG-SiR Synonyms SNAP-SiR CAS Number Related CAS Molecular Formula C40H40N8O4Si Molecular Weight 724

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg Product Name CP-BCN Synonyms SNAP2-BCNSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further