Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Size:10mg 421 SMILES [N-]=[N+]=NCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

421 SMILES [N-]=[N+]=NCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

forming a stable thioether linkage that resists hydrolysis and oxidation

Product Name Thalidomide-5'-O-PEG3-C2-acid Synonyms CAS Number n/a Related CAS Molecular Formula C22H26N2O10 Molecular Weight 478

Product Name DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C74H92N10O22 Molecular Weight 1473

a PEG linker

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Size:10mg 421 SMILES [N-]=[N+]=NCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine