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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg CP-BCN is a SNAP-tag substrate

SKU 5645342930
4.1
EUR445.00 EUR488.00

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Description

CP-BCN is a SNAP-tag substrate containg BCN moiety for click chemistry applications

Product Name Pomalidomide-C4-Br Synonyms Pomalidomide-4'-C4-Br CAS Number 2355289-79-9 Related CAS Molecular Formula C17H18BrN3O4 Molecular Weight 408

Protein degrader building block

19 Purity (HPLC) >= 95% Physical Appearance Dark Purple Solid Optical Properties Abs/Em Maxima: 555/585 nm Solubility DMSO

69 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg CP-BCN is a SNAP-tag substrateSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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