Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP propargyl CDCF) can passively diffuse into

CDCF) can passively diffuse into cells and is colorless and nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the fluorescent fluorophore

DOTA bifucational chelator containing an alkyne group

056 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons

796 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCC(O)=O)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP propargyl CDCF) can passively diffuse intoSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as