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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg Product Name MaP555-Alkyne Synonyms CAS

SKU 49793155577
4.2
USD495.00 USD539.00

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Description

Product Name MaP555-Alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C30H31N5O5S Molecular Weight 573

The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product

002 Purity (HPLC) >= 95% Solubility DMSO

[2H]C([2H])([2H])N(CCNC)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

785 Purity (HPLC) >= 95% Solubility DMSO

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Size:25mg Product Name MaP555-Alkyne Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by

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