Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) deuterium-labeled-bronic ester NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(NCCOCCOCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Fmoc-Val-Cit-PAB Synonyms Fmoc-VC-PAB-OH CAS Number 159858-22-7 Related CAS Molecular Formula C33H39N5O6 Molecular Weight 601

866 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

also referred to as the Cu(I)-catalyzed free click reaction

Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) deuterium-labeled-bronic ester NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through