Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP peg 458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC)

458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DOTA-butyne Synonyms CAS Number 2125661-62-1 Related CAS Molecular Formula C20H33N5O7 Molecular Weight 455

Journal of Medicinal Chemistry 2021

59 Purity (HPLC) >= 95% Physical Appearance Orange Solid Optical Properties Abs/Em Maxima: 503/509 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

611 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP peg 458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or