tert-butyl 4-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}piperazine-1-carboxylate click GW5074 reduces mHTT levels through

GW5074 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Cell Reports 2021

NCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C4-OH Synonyms Thalidomide-4'-O-acetamido-C4-OH CAS Number n/a Related CAS Molecular Formula C19H21N3O7 Molecular Weight 403

tert-butyl 4-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}piperazine-1-carboxylate click GW5074 reduces mHTT levels throughNitrogen Heterocycle Based Linker (NHBL). Binfunctional amine amine linker. Product Name tert butyl 4 {2 [4 (2 aminoethyl)piperazin 1 yl]ethyl}piperazine 1 carboxylate Synonyms CAS Number n a Related CAS Molecular Formula C17H35N5O2 Molecular Weight 341. 5 SMILES CC(C)(C)OC(=O)N1CCN(CCN2CCN(CCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory