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Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg It can be used in

SKU 38512760051
4.9
USD445.00 USD478.00

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Description

It can be used in many different diagnostic and therapeutic applications

PC-6 shows the largest fluorescence increase

CA-diAcFAM is a cell permeable HaloTag fluorescent ligand and can be used to label intracellular proteins (494Ex/526Em after hydrolysis)

191 Purity (HPLC) >= 95% Solubility DMSO

Product Name Biotin-PEG4-acid Synonyms CAS Number 721431-18-1 Related CAS Molecular Formula C21H37N3O8S Molecular Weight 491

Azide-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg It can be used inSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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