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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg NCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95%

SKU 34138268186
4.5
USD495.00 USD518.00

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Description

NCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name tert-butyl N-(2-{2-[4-(4-aminobutyl)piperazin-1-yl]ethoxy}ethyl)carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C17H36N4O3 Molecular Weight 344

66 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO

DBCO has been extensively used in copper-free click chemistry

… Chekler

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg NCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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