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336 SMILES CC(C)(C)OC(=O)CCCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C49H70N8O18 Molecular Weight 1059
Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid CAS Number 2488752-64-1 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434
Product Name Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H112FN11O27 Molecular Weight 1738
dCeMM2 (Compound 2) is a glue degrader
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg 336 SMILES CC(C)(C)OC(=O)CCCN1CCNCC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
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