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Haven’t got a glue: Protein surface variation for the design of molecular glue degraders
474 SMILES [N-]=[N+]=NCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
is highly sensitive
308 SMILES BrCCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
556 SMILES CC[C@H](CO)CC1=NC(NCC2=CC=C(C=C2)C2=CC=CC=N2)=C2N=CN(C(C)C)C2=N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
ispinesib Size:5mg Haven’t got a glue: ProteinIspinesib is an autophagic molecular degrader. It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule associated protein 1A 1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT). It is also a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1. 7 nM. Product Name ispinesib Synonyms 8F20, SB 715992 CAS Number 336113 53 2 Related CAS Molecular
