Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg 447 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCN1C(=O)C=CC1=O)C1=CC=C(O)C=C1O2 Purity (HPLC)

447 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCN1C(=O)C=CC1=O)C1=CC=C(O)C=C1O2 Purity (HPLC) 98% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

Product Name Pomalidomide-5'-C2-acid Synonyms CAS Number 2412056-29-0 Related CAS Molecular Formula C16H15N3O6 Molecular Weight 345

Product Name Pomalidomide-5'-C6-amine HCl Synonyms CAS Number n/a Related CAS 2097509-16-3 (free base) Molecular Formula C19H25ClN4O4 Molecular Weight 408

N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C9H12ClN Molecular Weight 175

02 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg 447 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCN1C(=O)C=CC1=O)C1=CC=C(O)C=C1O2 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a