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CC-647 is a Cereblon modulator
such as MRI contrast agents
Caprioglio
Product Name Thalidomide-OH Synonyms Thalidomide-4'-OH CAS Number 5054-59-1 Related CAS Molecular Formula C13H10N2O5 Molecular Weight 274
S wild type cells
DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) featured CC-647 is a Cereblon modulatorSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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