BG-N3 Size:100nmol Ubiquitination and degradation of SUMO1

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors

1126/sciadv

Product Name SiR-Azide Synonyms 6-SiR-Azide CAS Number N/A Related CAS N/A Molecular Formula C30H34N6O3Si Molecular Weight 554

01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

trisulfo is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins

BG-N3 Size:100nmol Ubiquitination and degradation of SUMO1SNAP tag is a self labeling protein derived from human O6 alkylguanine DNA alkyltransferase. At 20 kDa, SNAP tag is smaller than HaloTag (33 kDa), potentially reducing interference with the tagged proteins function. SNAP tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives, forming a stable thioether bonds that ensures durability for long term experiments or harsh conditions. SNAP tag can be used alongside other tags